Human GLP1R Full Length Protein (L260F), Flag,His Tag (Detergent), Unconjugated

Produktübersicht

• Artikelname: Human GLP1R Full Length Protein (L260F), Flag,His Tag (Detergent), Unconjugated
• Artikelnummer: ABS-GLR-H52D4-20UG
• Hersteller Artikelnummer: GLR-H52D4-20ug
• Alternativnummer: ABS-GLR-H52D4-20UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

This gene encodes a 7transmembrane protein that functions as a receptor for glucagonlike peptide 1 (GLP1) hormone, which stimulates glucoseinduced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP1 and GLP1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 66.5 kDa
• Tag: N-Flag & C-10*His
• NCBI: 43220
• Puffer: 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5
• Formulierung: Liquid
• Target-Kategorie: GLP1R

Bilder

Immobilized Human GLP1R FullLength Protein, Flag,His Tag (Cat. No. GLR-H52D4) at 5 µg/mL (100 µL/well) on a Nickel Coated plate (Cat. No. SP-16) can bind Dulaglutide with a linear range of 0.5-16 ng/mL (QC tested).

Immobilized Human GLP1R FullLength Protein (L260F), Flag,His Tag (Cat. No. GLR-H52D4) at 5 µg/mL (100 µL/well) can bind Glutazumab with a linear range of 0.06-1 ng/mL (Routinely tested).

GLR-H52D4-20ug