Vascular cell adhesion protein 1 (VCAM1) is also known as CD106, INCAM100 and L1CAM, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. VCAM1 / CD106 contains 7 Iglike C2type (immunoglobulinlike) domains. CD106 / VCAM1 is expressed on inflammed vascular endothelium, as well as on macrophagelike and dendritic cell types in both normal and inflammed tissue. L1CAM / VCAM1 is Important in cellcell recognition and appears to function in leukocyteendothelial cell adhesion. CD106 / VCAM1 interacts with the beta1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1 / VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. INCAM100 / VCAM1 binds to ECMVD capsid proteins and acts as a receptor for this virus. - Proteine/Peptide
Immobilized GMP Human VCAM-1 Protein, Fc Tag (Cat. No. GMP-VC1H25) at 5 µg/mL (100 µL/well) can bind Biotinylated Human ITGA4&ITGB1 Heterodimer Protein, His,Avitag&Tag Free (Cat. No. IT1-H82W1) with a linear range of 2-63 ng/mL (Routinely tested).
GMP Human VCAM-1 Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
GMP-VC1H25-100ug
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