Human GPR146 Full Length Protein, His,Flag Tag (Detergent), Unconjugated, E. coli 100 ug

Produktübersicht

• Artikelname: Human GPR146 Full Length Protein, His,Flag Tag (Detergent), Unconjugated, E. coli 100 ug
• Artikelnummer: ABS-GP6-H51D3-100UG
• Hersteller Artikelnummer: GP6-H51D3-100ug
• Alternativnummer: ABS-GP6-H51D3-100UG
• Hersteller: AcroBiosystems
• Wirt: E. coli
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

GPR146 (G ProteinCoupled Receptor 146) is a class A orphan G proteincoupled receptor (GPCR) . GPR146 is encoded by the GPR146 gene located on human chromosome 5 (5q12.1) and is broadly expressed in metabolic tissues, including the liver, pancreas, and adipose tissue, suggesting potential roles in energy homeostasis.Emerging evidence links GPR146 to lipid and glucose metabolism. For instance, in vivo studies in rodents indicate that GPR146 knockdown reduces plasma cholesterol and triglyceride levels, implicating it in lipid regulation. Additionally, GPR146 may modulate insulin secretion via interactions with pancreatic betacells, hinting at relevance in diabetes pathophysiology.(PubMed,31778654, PubMed, 38503280) - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 42.3 kDa
• Tag: N-10*His & C-Flag
• NCBI: 96
• Puffer: 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5
• Reinheit: 90%
• Formulierung: Liquid
• Target-Kategorie: GPR146

Bilder

Immobilized Human GPR146 Full Length Protein, His,Flag Tag (Cat. No. GP6-H51D3) at 1 µg/mL (100 µL/well) can bind Anti-GPR146 Antibody, Rabbit IgG with a linear range of 1-78 ng/mL (QC tested).