APC-Labeled Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Tetramer Protein
Artikelnummer:
ABS-HL1-HA2H8-25TESTS
Hersteller Artikelnummer:
HL1-HA2H8-25tests
Alternativnummer:
ABS-HL1-HA2H8-25TESTS
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
APC
NYESO1, which is also wellknown as New York esophageal squamous cell carcinoma 1, is an efficient target for cancer immunotherapy. This antigen is a member of cancertestis antigens (CTAs) and is highly expressed in various cancers, including melanoma, ovarian, cervical cancer, etc. Adoptive T cell therapy with HLAA2 restricted NYESO1 transduced CD8+ T cells has improved the clinical response rates and overall survival of treatmentrefractory melanoma patients. The Human HLAA*0201 NYESO1 (SLLMWITQV) complex protein is a complex of HLAA*0201 of the MHC Class I, B2M and SLLMWITQV peptide of the NYESO1. - Proteine/Peptide