Biotinylated Human HLA-A*02:01&B2M&gp100 (YLEPGPVTA) Complex Protein (Monomer, MALS verified)

Artikelnummer: ABS-HLG-H82E6-25UG
Artikelname: Biotinylated Human HLA-A*02:01&B2M&gp100 (YLEPGPVTA) Complex Protein (Monomer, MALS verified)
Artikelnummer: ABS-HLG-H82E6-25UG
Hersteller Artikelnummer: HLG-H82E6-25ug
Alternativnummer: ABS-HLG-H82E6-25UG
Hersteller: AcroBiosystems
Wirt: Human
Kategorie: Proteine/Peptide
Spezies Reaktivität: Human
Konjugation: Biotin
Glycoprotein 100, is also well known as gp100 and Melanocyte protein PMEL. This antigen is a melanocytespecific type I transmembrane glycoprotein and composed of 661 amino acids. Glycoprotein 100 is related to the tumor regression in metastatic melanoma patients after adoptive therapy, by which its epitopes being recognized by tumor lymphocytes and Tcells. The gp100280-288(YLEPGPVTA) was originally shown to be recognized by HLAA*0201 tumorinfiltrating lymphocytes from melanoma patients, and therefore it is widely been studied in TCR T studies. The Human HLAA*0201 gp100 (YLEPGPVTA) complex protein is a complex of HLAA*0201 of the MHC Class I, B2M and YLEPGPVTA peptide of the gp100. - Proteine/Peptide
Molekulargewicht: 36.0 kDa and 13.7 kDa
Tag: C-10*His & C-Avi
NCBI: 59606
Puffer: PBS, pH7.4
Reinheit: 95%
Formulierung: Powder
Target-Kategorie: HLA-A*02:01 & B2M & gp100 (YLEPGPVTA)
Immobilized Biotinylated Human HLA-A*02:01&B2M&gp100 (YLEPGPVTA) Complex Protein (Cat. No. HLG-H82E6) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Anti-HLA class I Antibody, Human IgG1 (W6/32) with a linear range of 0.1-4 ng/mL (QC tested).
Immobilized Biotinylated Human HLA-A*02:01&B2M&gp100 Protein (Cat. No. HLG-H82E6) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Anti-B2M Antibody, Human IgG1 with a linear range of 0.1-2 ng/mL (Routinely tested).
Biotinylated Human HLA-A*02:01&B2M&gp100 (YLEPGPVTA) Complex Protein on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.