Biotinylated Human HLA-A*03:01&B2M&Survivin Mut (RISTFKNWPK) Complex Protein (Monomer, MALS verified)

Produktübersicht

• Artikelname: Biotinylated Human HLA-A*03:01&B2M&Survivin Mut (RISTFKNWPK) Complex Protein (Monomer, MALS verified)
• Artikelnummer: ABS-HLT-H82E3-25UG
• Hersteller Artikelnummer: HLT-H82E3-25ug
• Alternativnummer: ABS-HLT-H82E3-25UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Biotin

Produktbeschreibung

The peptide RISTFKNWPK, derived from a survivin mutant, is presented by the HLAA*03:01/beta2m complex and serves as a promising neoantigen target. Its presentation enables cytotoxic T lymphocytes (CTLs) to recognize and attack tumor cells overexpressing this mutated survivin variant, which is often associated with cancer cell survival and therapy resistance, offering a potential avenue for specific immunotherapy. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 36.1 kDa and 11.7 kDa
• Tag: C-10*His & C-Avi
• NCBI: 04439
• Puffer: PBS, pH7.4
• Reinheit: 90%
• Formulierung: Powder
• Target-Kategorie: HLA-A*0301 & B2M & Survivin Mut (RISTFKNWPK)

Bilder

Immobilized Anti-HLA class I Antibody, Human IgG1 (W6/32) at 1 µg/mL (100 µL/well) can bind Biotinylated Human HLA-A*03:01&B2M&Survivin Mut (RISTFKNWPK) Complex Protein (Cat. No. HLT-H82E3) with a linear range of 0.1-4 ng/mL (QC tested).

Immobilized Biotinylated Human HLA-A*03:01&B2M&Survivin Mut (RISTFKNWPK) Complex Protein (Cat. No. HLT-H82E3) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Anti-HLA class I Antibody, Human IgG1 (W6/32) with a linear range of 0.2-3 ng/mL (Routinely tested).

Biotinylated Human HLA-A*03:01&B2M&Survivin Mut (RISTFKNWPK) Complex Protein on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.