APC-Labeled Human HLA-A*02:01&B2M&hTERT (ILAKFLHWL) Tetramer Protein

Produktübersicht

• Artikelname: APC-Labeled Human HLA-A*02:01&B2M&hTERT (ILAKFLHWL) Tetramer Protein
• Artikelnummer: ABS-HLT-HA2H7-25UG
• Hersteller Artikelnummer: HLT-HA2H7-25ug
• Alternativnummer: ABS-HLT-HA2H7-25UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: APC

Produktbeschreibung

hTERT (human Telomerase Reverse Transcriptase), the catalytic subunit of telomerase, maintains telomere length to drive tumor cells unlimited proliferation. It is highly expressed in ~8590% of cancers but silenced in most normal somatic cells. The peptide ILAKFLHWL (from hTERT residues 540548) acts as a tumorspecific antigen. It binds to MHC class I molecule HLAA0201 to form a surface complex on tumors, activating cytotoxic T lymphocytes (CTLs). The Human HLAA*0201 hTERT (ILAKFLHWL) complex protein is a complex of HLAA*0201 of the MHC Class I, B2M, and ILAKFLHWL peptide of the hTERT. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 36.3 kDa and 11.7 kDa
• Tag: C-10*His
• NCBI: 59606
• Puffer: PBS, 1% BSA, pH7.4
• Formulierung: Powder
• Target-Kategorie: HLA-A*0201 & B2M & hTERT (ILAKFLHWL)

Bilder

HLT-HA2H7-25ug