Human HVEM / TNFRSF14 Protein, Mouse IgG2a Fc Tag (MALS verified), Unconjugated

Produktübersicht

• Artikelname: Human HVEM / TNFRSF14 Protein, Mouse IgG2a Fc Tag (MALS verified), Unconjugated
• Artikelnummer: ABS-HVM-H5257-1MG
• Hersteller Artikelnummer: HVM-H5257-1mg
• Alternativnummer: ABS-HVM-H5257-1MG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

Herpesvirus entry mediator (HVEM) is also known as TNFRSF14, TR2 (TNF receptorlike molecule) and ATAR (another TRAF associated receptor), is a type I membrane protein belonging to the TNF/NGF receptor superfamily. HVEM expression has been detected in peripheral blood T cells, B cells, monocytes and in various tissues enriched in lymphoid cells. The extracellular domain of HVEM has been shown to interact directly with the herpes simplex virus envelope glycoprotein D (gD). Two TNF superfamily ligands, including the secreted TNFbeta (lymphotoxin alpha) and the membrane protein LIGHT (lymphotoxins, exhibits inducible expression, and competes with HSV glycoprotein D for HVEM, a receptor expressed by T lymphocytes), have been shown to be the cellular ligands for HVEM. Besides HVEM, LIGHT can also interact with LTbetaR, the receptor for lymphotoxin alphabeta heterotrimer. The role of the HVEM LIGHT /LTbeta receptor ligand pair in immune function and herpesvirus pathobiology remains to be elucidated. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 44.2 kDa
• Tag: C-mFc(mIgG2a)
• NCBI: 92956
• Puffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
• Reinheit: 95%
• Formulierung: Powder
• Target-Kategorie: HVEM

Bilder

Immobilized Human LIGHT, Fc Tag (active trimer) (MALS verified) (Cat. No. LIT-H5269) at 5 µg/mL (100 µL/well) can bind Human HVEM, Mouse IgG2a Fc Tag (Cat. No. HVM-H5257) with a linear range of 0.4-6 ng/mL (QC tested).

Immobilized Biotinylated Human BTLA (31-150), His,Avitag (Cat. No. BTA-H82E4) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Human HVEM, Mouse IgG2a Fc Tag (Cat. No. HVM-H5257) with a linear range of 0.1-8 ng/mL (Routinely tested).

Human HVEM, Mouse IgG2a Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.