Human IFN-alpha/beta R2 Protein, His Tag (MALS verified), Unconjugated

Artikelnummer: ABS-IF2-H5224-100UG
Artikelname: Human IFN-alpha/beta R2 Protein, His Tag (MALS verified), Unconjugated
Artikelnummer: ABS-IF2-H5224-100UG
Hersteller Artikelnummer: IF2-H5224-100ug
Alternativnummer: ABS-IF2-H5224-100UG
Hersteller: AcroBiosystems
Wirt: Human
Kategorie: Proteine/Peptide
Spezies Reaktivität: Human
Konjugation: Unconjugated
Interferon alpha/beta receptor 2 (IFNAR2) is also known as IFNalpha binding protein, IFNalpha/beta receptor 2, Type I interferon receptor 2, IFNABR and IFNARB, which is a singlepass type I membrane protein and belongs to the type II cytokine receptor family. IFNAR2 can associate with IFNAR1 to form the type I interferon receptor. IFNAR2 is a receptor for interferons alpha and beta.IFNAR2 involves in IFNmediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 of IFNAR2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 of IFNAR2 is a potent inhibitor of type I IFN receptor activity.Genetic variations in IFNAR2 influence susceptibility to hepatitis B virus (HBV) infection. - Proteine/Peptide
Molekulargewicht: 25.8 kDa
Tag: C-8*His
NCBI: 48551
Puffer: PBS, pH7.4
Reinheit: 95%
Formulierung: Powder
Target-Kategorie: IFN-alpha/beta R2
Human IFNAR2, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
IF2-H5224-100ug
Immobilized Human IFNAR2, His Tag (Cat. No. IF2-H5224) at 5 µg/mL (100 µL/well) can bind Human IFN-alpha 2a (R46K) Protein, Fc Tag (Cat. No. IFA-H5253) with a linear range of 1-40 ng/mL (Routinely tested).
Immobilized Human IFNAR2, His Tag (Cat. No. IF2-H5224) at 5 µg/mL (100 µL/well) can bind Human IFN-beta Protein, Fc Tag (Cat. No. IFB-H5254) with a linear range of 0.03-2 ng/mL (Routinely tested).