Human IL-11 Protein, Fc Tag, low Endotoxin (MALS verified), Unconjugated
Artikelnummer:
ABS-IL1-H5269-500UG
Hersteller Artikelnummer:
IL1-H5269-500ug
Alternativnummer:
ABS-IL1-H5269-500UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Interleukin11 (IL11) is a pleiotropic cytokine that stimulates megakaryocytopoiesis, resulting in increased production of platelets, as well as activating osteoclasts, inhibiting epithelial cell proliferation and apoptosis, and inhibiting macrophage mediator production. These functions may be particularly important in mediating the hematopoietic, osseous and mucosal protective effects of IL11. The cytokine also possesses antiinflammatory activity, and has been proposed as a therapeutic agent in the treatment of chronic inflammatory diseases, such as Crohns disease and rheumatoid arthritis. Although IL11 was initially believed to be restricted to mammals, subsequent studies demonstrated it to be expressed in fish. Despite close similarity in gene structure and conservation of key amino acids between fish and mammalian IL11, they share relatively low overall amino acid identity and may not necessarily be functionally analogous. - Proteine/Peptide
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Reinheit:
95%
Formulierung:
Powder
Target-Kategorie:
IL-11
Immobilized Human IL-11 R alpha, His Tag (Cat. No. ILR-H52H5) at 5 µg/mL (100 µL/well) can bind Human IL-11, Fc Tag (Cat. No. IL1-H5269) with a linear range of 0.2-10 ng/mL (QC tested).
Immobilized Human IL-11, Fc Tag (Cat. No. IL1-H5269) at 5 µg/mL (100 µL/well) can bind Human IL-11 R alpha, His Tag (Cat. No. ILR-H52H5) with a linear range of 0.008-0.5 µg/mL (Routinely tested).
Human IL-11, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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