Human IL-13 Protein, Fc Tag, low endotoxin (MALS verified), Unconjugated

Produktübersicht

• Artikelname: Human IL-13 Protein, Fc Tag, low endotoxin (MALS verified), Unconjugated
• Artikelnummer: ABS-IL3-H5256-500UG
• Hersteller Artikelnummer: IL3-H5256-500ug
• Alternativnummer: ABS-IL3-H5256-500UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

Interleukin 13 (IL13) is also known as ALRH, BHR1and P600, is a singlechain glycosylated polypeptide, and is a cytokine critical in regulating inflammatory and immune responses. IL13 is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL13 induces its effects through a multisubunit receptor that includes the alpha chain of the IL4 receptor (IL4Ralpha) and at least one of two known IL13specific binding chains. The functions of IL13 overlap considerably with those of IL4, especially with regard to changes induced on hematopoietic cells, but these effects are probably less important given the more potent role of IL4. IL13 induces matrix metalloproteinases (MMPs) as part of a mechanism that protects against excessive allergic inflammation that predisposes to asphyxiation. IL13 induces many features of allergic lung disease, including airway hyperresponsiveness, goblet cell metaplasia and mucus hypersecretion, which all contribute to airway obstruction. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 38.8 kDa
• Tag: C-Fc
• NCBI: 53823
• Puffer: Tris with Glycine, Arginine and NaCl, pH7.5
• Reinheit: 90%
• Formulierung: Powder
• Target-Kategorie: IL-13

Bilder

IL3-H5256-500ug

Immobilized Human IL-13, Fc Tag (Cat. No. IL3-H5256) at 5 µg/mL (100 µL/well) can bind Monoclonal Anti-Human IL-13 Antibody, Human IgG4 with a linear range of 0.4-6 ng/mL (QC tested).

Immobilized Human IL-13, Fc Tag (Cat. No. IL3-H5256) at 5 µg/mL (100 µL/well) can bind Human IL-13 R alpha 2, His Tag (Cat. No. IL2-H52H5) with a linear range of 0.02-0.313 µg/mL (Routinely tested).

Human IL-13, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.