Human IL-17 RA / CD217 Protein, His Tag, Unconjugated
Artikelnummer:
ABS-ILA-H5222-100UG
Hersteller Artikelnummer:
ILA-H5222-100ug
Alternativnummer:
ABS-ILA-H5222-100UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Interleukin 17 receptor A (IL17RA) is also known as cluster of differentiation w217 (CDw217), is a proinflammatory cytokine secreted by activated Tlymphocytes, belong to ubiquitous type I membrane glycoprotein, and binds with low affinity to interleukin 17A (IL17A). IL 17R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested . IL 17RA associates with IL 17RC to form a signaling receptor complex for IL 17 and IL 17F . Ligand and IL 17RA ligation promotes T cell activation and the production of IL 6, GCSF, SCF, and multiple proinflammatory chemokines. Defects in IL17RA are the cause of familial candidiasis type 5 (CANDF5). - Proteine/Peptide
Immobilized Human IL17A, Tag Free (Cat. No. ILA-H5219) at 2 µg/mL (100 µL/well) can bind Human IL-17 RA, His Tag (Cat. No. ILA-H5222) with a linear range of 0.4-6 ng/mL (QC tested).
Human IL-17 RA, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 98%.
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