Mouse IL-2 R alpha / CD25 Protein, His Tag (MALS verified), Unconjugated, Human

Artikelnummer: ABS-ILA-M52H9-100UG
Artikelname: Mouse IL-2 R alpha / CD25 Protein, His Tag (MALS verified), Unconjugated, Human
Artikelnummer: ABS-ILA-M52H9-100UG
Hersteller Artikelnummer: ILA-M52H9-100ug
Alternativnummer: ABS-ILA-M52H9-100UG
Hersteller: AcroBiosystems
Wirt: Human
Kategorie: Proteine/Peptide
Spezies Reaktivität: Mouse
Konjugation: Unconjugated
Interleukin2 receptor subunit alpha (IL2RA) is also known as IL2R subunit alpha, IL2RA, IL2RA, TAC antigen, p55, CD antigen CD25, is a type I transmembrane glycoprotein. IL2RA is expressed on activated T cells and regulatory T cells, and is capable of binding IL2 with low affinity by itself. However, a ligandinduced high affinity heterotrimeric receptor complex is produced when IL2RA is associated noncovelently with the IL2 receptor beta and gamma chain, and subsequently initiates the intacellular signal pathways such as MAPK or JAK/STAT. On dendritic cells (DC), CD25 has been previously regarded as an activation marker, while both murine and human DC can express CD25, they do not express the betachain of the IL2 receptor, which is indispensable for the execution of IL2 signaling. - Proteine/Peptide
Molekulargewicht: 26.6 kDa
Tag: C-10*His
NCBI: 01590
Puffer: PBS, pH7.4
Reinheit: 90%
Formulierung: Powder
Target-Kategorie: IL-2 R alpha
ILA-M52H9-100ug
Immobilized Biotinylated Human IL-2, Fc Tag, Avi Tag (Cat. No. IL2-H82F3) at 5 µg/mL (100 µL/well) on Streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate, can bind Mouse IL-2 R alpha, His Tag (Cat. No. ILA-M52H9) with a linear range of 5-40 ng/mL (QC tested).
Immobilized Mouse IL-2 R alpha, His Tag (Cat. No. ILA-M52H9) at 5 µg/mL (100 µL/well) can bind Biotinylated Human IL-2, Fc Tag, Avi Tag (Cat. No. IL2-H82F3) with a linear range of 0.6-10 ng/mL (Routinely tested).
Mouse IL-2 R alpha, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.