Human IL-37 / IL-1F7 Protein, His Tag, Unconjugated, E. coli

Produktübersicht

• Artikelname: Human IL-37 / IL-1F7 Protein, His Tag, Unconjugated, E. coli
• Artikelnummer: ABS-ILB-H51H5-50UG
• Hersteller Artikelnummer: ILB-H51H5-50ug
• Alternativnummer: ABS-ILB-H51H5-50UG
• Hersteller: AcroBiosystems
• Wirt: E. coli
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

Interleukin1 family member 7 (IL1F7b) ,a member of the IL1 family, is aslo known as interleukin37, interleukin1 homolog 4 (IL1H4), interleukin1 zeta (IL1 zeta) and interleukin1related protein, which can interact with SMAD3 and bind to IL18R1, but not to IL1R1, with lower affinity than IL18. IL1F7b is a suppressor of innate inflammatory and immune responses involved in curbing excessive inflammation. This function requires SMAD3. Therefore,IL1F7b can suppress, or reduce, proinflammatory cytokine production, including IL1A and IL6, as well as CCL12, CSF1, CSF2, CXCL13, IL1B, IL23A and IL1RN, but spare antiinflammatory cytokines. Furthermore,IL1F7b can also inhibit dendritic cell activation. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 20.1 kDa
• Tag: C-10*His
• NCBI: 9
• Puffer: PBS, pH7.4
• Reinheit: 95%
• Formulierung: Powder
• Target-Kategorie: IL-37

Bilder

Human IL-37, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.