Human IL-17 RA&IL-17 RC Heterodimer Protein, Fc Tag&Fc Tag (MALS verified), Unconjugated

Produktübersicht

• Artikelname: Human IL-17 RA&IL-17 RC Heterodimer Protein, Fc Tag&Fc Tag (MALS verified), Unconjugated
• Artikelnummer: ABS-ILC-H5257-100UG
• Hersteller Artikelnummer: ILC-H5257-100ug
• Alternativnummer: ABS-ILC-H5257-100UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

Also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC. Cytokine binding triggers homotypic interaction of IL17RA and IL17RC chains with TRAF3IP2 adapter, leading to TRAF6mediated activation of NFkappaB and MAPkinase pathways, ultimately resulting in transcriptional activation of cytokines, chemokines, antimicrobial peptides and matrix metalloproteinases, with potential strong immune inflammation. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 60.0 kDa (IL-17 RA) & 75.7 kDa (IL-17 RC)
• Tag: C-Fc | C-Fc
• NCBI: 96
• Puffer: PBS, pH7.4
• Reinheit: 95%
• Formulierung: Powder
• Target-Kategorie: IL-17 RA & IL-17 RC

Bilder

Immobilized Human IL-17A&IL-17F Heterodimer Protein, His Tag&Strep II Tag at 2 µg/mL (100 µL/well) can bind Human IL17RA & IL17RC Protein, Fc Tag&Fc Tag (Cat. No. ILC-H5257) with a linear range of 1-20 ng/mL (QC tested).

Immobilized Human IL17A, Tag Free at 2 µg/mL (100 µL/well) can bind Human IL17RA & IL17RC Protein, Fc Tag&Fc Tag (Cat. No. ILC-H5257) with a linear range of 0.6-10 ng/mL (Routinely tested).

Human IL17RA&IL17RC Protein, Fc Tag&Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

ILC-H5257-100ug