Cynomolgus IL-10 R alpha / CD210 Protein, Fc Tag, Unconjugated, Human

Produktübersicht

• Artikelname: Cynomolgus IL-10 R alpha / CD210 Protein, Fc Tag, Unconjugated, Human
• Artikelnummer: ABS-ILR-C5256-1MG
• Hersteller Artikelnummer: ILR-C5256-1mg
• Alternativnummer: ABS-ILR-C5256-1MG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Monkey
• Konjugation: Unconjugated

Produktbeschreibung

Interleukin10 receptor subunit alpha (IL10 R alpha ) is a cell surface receptor for the cytokine IL10 that participates in IL10 mediated antiinflammatory functions, limiting excessive tissue disruption caused by inflammation. Upon binding to IL10, induces a conformational change in IL10RB, allowing IL10RB to bind IL10 as well.In turn, the heterotetrameric assembly complex, composed of two subunits of IL10RA and IL10RB, activates the kinases JAK1 and TYK2 that are constitutively associated with IL10RA and IL10RB respectively.These kinases then phosphorylate specific tyrosine residues in the intracellular domain in IL10RA leading to the recruitment and subsequent phosphorylation of STAT3 - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 50.8 kDa
• Tag: C-Fc
• NCBI: 005579838
• Puffer: PBS, pH7.4
• Reinheit: 90%
• Formulierung: Powder
• Target-Kategorie: IL-10 R alpha

Bilder

ILR-C5256-1mg

Immobilized Human IL-10, His Tag (Cat. No. IL0-H4248) at 5 µg/mL (100 µL/well) can bind Cynomolgus IL-10 R alpha / CD210, Fc Tag (Cat. No. ILR-C5256) with a linear range of 0.2-2 ng/mL (QC tested).

Cynomolgus IL-10 R alpha Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.