Biotinylated Cynomolgus IL-23 R Protein, His,Avitag(TM) (MALS & SPR verified), Human

Artikelnummer: ABS-ILR-C82E4-25UG
Artikelname: Biotinylated Cynomolgus IL-23 R Protein, His,Avitag(TM) (MALS & SPR verified), Human
Artikelnummer: ABS-ILR-C82E4-25UG
Hersteller Artikelnummer: ILR-C82E4-25ug
Alternativnummer: ABS-ILR-C82E4-25UG
Hersteller: AcroBiosystems
Wirt: Human
Kategorie: Proteine/Peptide
Spezies Reaktivität: Monkey
Konjugation: Biotin
Interleukin 23 receptor (IL23R) is a type I cytokine receptor, and IL23R pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. Also, IL23R associates constitutively with Janus kinase 2 (JAK2), and binds to transcription activator STAT3 in a liganddependent manner. Furthermore, IL23R mediates Tcells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the JakStat signaling cascade. As for IL23, it may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. - Proteine/Peptide
Molekulargewicht: 41.7 kDa
Tag: C-10*His & C-Avi
NCBI: 7
Puffer: PBS, pH7.4
Reinheit: 95%
Formulierung: Powder
Target-Kategorie: IL-23 R