Human IL-4 R alpha & IL-13 R alpha 1 Protein, Fc Tag&Fc Tag (MALS verified), Unconjugated
Artikelnummer:
ABS-ILR-H525B-100UG
Hersteller Artikelnummer:
ILR-H525b-100ug
Alternativnummer:
ABS-ILR-H525B-100UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Interleukin 4 Receptor (IL4R) also known as CD124, IL4Ralpha and BSF receptor, is a type I cytokine receptor produced by activated Th2 cells and mast cells, and plays an important role in Th2biased immune responses, alternative macrophage activation, mucosal immunity, allergic inflammation, tumor progression, and atherogenesis. A soluble form of the encoded IL4R protein can be produced by an alternate splice variant or by proteolysis of the membranebound protein, and this soluble form can inhibit IL4mediated cell proliferation and IL5 upregulation by Tcells. IL4R can alternatively associate with IL13Ra1 to form the type II receptor which is responsive to both IL4 and IL13. Interleukin4 receptor has been shown to interact with SHC1. - Proteine/Peptide
Immobilized Human IL-4 R alpha & IL-13 R alpha 1 Protein, Fc Tag&Fc Tag (Cat. No. ILR-H525b) at 5 µg/mL (100 µL/well) can bind Human IL-4, His Tag (Cat. No. IL4-H52H9) with a linear range of 0.6-5 ng/mL (QC tested).
Human IL-4 R alpha & IL-13 R alpha 1 Protein, Fc Tag&Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Biotinylated Human IL-13, His,Avitag (Cat. No. IL3-H82E5) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Human IL-4 R alpha & IL-13 R alpha 1 Protein, Fc Tag&Fc Tag (Cat. No. ILR-H525b) with a linear range of 0.6-20 ng/mL (Routinely tested).
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