Rabbit IL-23 R Protein, His Tag (MALS & SPR verified), Unconjugated, Human

Artikelnummer: ABS-ILR-R52H6-1MG
Artikelname: Rabbit IL-23 R Protein, His Tag (MALS & SPR verified), Unconjugated, Human
Artikelnummer: ABS-ILR-R52H6-1MG
Hersteller Artikelnummer: ILR-R52H6-1mg
Alternativnummer: ABS-ILR-R52H6-1MG
Hersteller: AcroBiosystems
Wirt: Human
Kategorie: Proteine/Peptide
Spezies Reaktivität: Rabbit
Konjugation: Unconjugated
Interleukin 23 receptor (IL23R) is a type I cytokine receptor, and IL23R pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. Also, IL23R associates constitutively with Janus kinase 2 (JAK2), and binds to transcription activator STAT3 in a liganddependent manner. Furthermore, IL23R mediates Tcells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the JakStat signaling cascade. As for IL23, it may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. - Proteine/Peptide
Molekulargewicht: 39.7 kDa
Tag: C-10*His
NCBI: 069934396
Puffer: PBS, pH7.4
Reinheit: 95%
Formulierung: Powder
Target-Kategorie: IL-23 R
Rabbit IL-23 R Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.