Feline Insulin R / CD220 (28-956) Protein, His Tag (HPLC verified), Unconjugated, Human

Artikelnummer: ABS-INR-C52H3-1MG
Artikelname: Feline Insulin R / CD220 (28-956) Protein, His Tag (HPLC verified), Unconjugated, Human
Artikelnummer: ABS-INR-C52H3-1MG
Hersteller Artikelnummer: INR-C52H3-1mg
Alternativnummer: ABS-INR-C52H3-1MG
Hersteller: AcroBiosystems
Wirt: Human
Kategorie: Proteine/Peptide
Spezies Reaktivität: Feline
Konjugation: Unconjugated
Insulin receptor (INSR) is also known as CD antigen CD220, which can be cleaved into the following 2 chains: Insulin receptor subunit alpha and Insulin receptor subunit beta. INSR is a tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains carry the insulinbinding regions, while the beta chains carry the kinase domain. Forms a hybrid receptor with IGF1R, the hybrid is a tetramer consisting of 1 alpha chain and 1 beta chain of INSR and 1 alpha chain and 1 beta chain of IGF1R. In addition to binding insulin, the insulin receptor can bind insulinlike growth factors (IGFI and IGFII). Isoform Short of INSR has a higher affinity for IGFII binding. When present in a hybrid receptor with IGF1R, INSR binds IGF1. - Proteine/Peptide
Molekulargewicht: 107.5 kDa
Tag: C-10*His
NCBI: 0
Puffer: PBS, pH7.4
Reinheit: 95%
Formulierung: Powder
Target-Kategorie: Insulin R
Feline Insulin R (28-956) Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.