Integrins are transmembrane proteins that mediate interactions between adhesion molecules on adjacent cells and/or the extracellular matrix (ECM). Integrins have diverse roles in several biological processes including cell migration during development and wound healing, cell differentiation, and apoptosis. Their activities can also regulate the metastatic and invasive potential of tumor cells. Integrin alpha 4 beta 1(Alpha4/beta1) is receptors for fibronectin. Integrin alpha4/beta1 is a receptor for VCAM1 and recognizes the sequence QIDS in VCAM1. - Proteine/Peptide
Immobilized Natalizumab at 1 µg/mL (100 µL/well) can bind Biotinylated Human ITGA4&ITGB1 Heterodimer Protein, His,Avitag&Tag Free (Cat. No. IT1-H82W1) with a linear range of 2-31 ng/mL (QC tested).
Immobilized Human VCAM-1, His Tag (Cat. No. VC1-H5224) at 5 µg/mL (100 µL/well) can bind Biotinylated Human ITGA4&ITGB1 Heterodimer Protein, His,Avitag&Tag Free (Cat. No. IT1-H82W1) with a linear range of 0.01-0.156 µg/mL (Routinely tested).
Biotinylated Human ITGA4&ITGB1 Heterodimer Protein, His,Avitag&Tag Free on SDS-PAGE under non-reducing (NR) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
IT1-H82W1-200ug
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