Human Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein, His Tag&Tag Free (MALS verified), Unconjugated
Artikelnummer:
ABS-IT3-H52E3-1MG
Hersteller Artikelnummer:
IT3-H52E3-1mg
Alternativnummer:
ABS-IT3-H52E3-1MG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Integrin alphaV/beta3 (ITGAV:ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrins alphaIIb/beta3 and alphaV/beta3 recognize the sequence RGD in a wide array of ligands. Also, Integrin alphaV/beta3 acts as a receptor for herpes virus 8/HHV8, coxsackievirus A9, Hantaan virus, cytomegalovirus/HHV5, human metapneumovirus, human parechovirus 1 and west nile virus. Furthermore, in case of HIV1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposis sarcoma lesions. - Proteine/Peptide
Immobilized Human Fibronectin at 2 µg/mL (100 µL/well) can bind Human ITGAV&ITGB3 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT3-H52E3) with a linear range of 0.01-0.3 µg/mL (QC tested).
Immobilized Human Vitronectin at 2 µg/mL (100 µL/well) can bind Human ITGAV&ITGB3 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT3-H52E3) with a linear range of 10-156 ng/mL (Routinely tested).
Human ITGAV&ITGB3 Heterodimer Protein, His Tag&Tag Free on SDS-PAGE under non-reducing (NR) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
IT3-H52E3-1mg
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