Human Kremen-2 CUB Domain Protein, His Tag, Unconjugated
Artikelnummer:
ABS-KR2-H52H4-1MG
Hersteller Artikelnummer:
KR2-H52H4-1mg
Alternativnummer:
ABS-KR2-H52H4-1MG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Kremen2 (Krm2) plays an important role in embryonic development, bone formation, and tumorigenesis as a crucial regulator of classical Wnt/betacatenin signaling pathway. Krm1 and its paralog Krm2 share the ability to bind Dkk1 and inhibit Wnt signaling, both processes previously shown to rely on the extracellular domain. Previous studies have shown that Krm2 may be involved in embryonic development, bone formation, neural ridge formation and tumorigenesis and could be a biomarker of grading and a potential therapeutic target in gastric cancer. - Proteine/Peptide
