The fourth member of the leucinerich repeatcontaining GPCR family (LGR4, frequently referred to as GPR48) together with its family members LGR5 and 6, bind to Rspondins (RSPOs)1-4 and result in Wnt signaling potentiation. In addition, LGR4 (as well as LGR5 and 6) is implicated in multiple cancers and promotes invasion and metastasis in colorectal, prostate, and cervical cancer cell lines. - Proteine/Peptide
Immobilized Human R-Spondin 3 at 2 µg/mL (100 µL/well) can bind Human LGR4, His Tag (Cat. No. LG4-H52H3) with a linear range of 10-78 ng/mL (QC tested).
Human LGR4, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 85%.
LG4-H52H3-1mg
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