Human LILRA4 / CD85g / ILT7 Protein, His Tag (MALS verified), Unconjugated

Produktübersicht

• Artikelname: Human LILRA4 / CD85g / ILT7 Protein, His Tag (MALS verified), Unconjugated
• Artikelnummer: ABS-LI4-H5243-100UG
• Hersteller Artikelnummer: LI4-H5243-100ug
• Alternativnummer: ABS-LI4-H5243-100UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

Leukocyte immunoglobulinlike receptor subfamily A member 4 (LILRA4/ILT7/CD85g) is a marker of plasmacytoid dendritic cells (pDCs), which are reported to be a major source of the abnormally high levels of IFNalpha associated with autoimmune diseases. Targeting LILRA4 with therapeutic antibodies to promote killing of these IFNalphaproducing pDCs is being investigated as a novel approach to alleviating the symptoms of autoimmune diseases. LILRA4 is an immunoglobulinlike protein preferentially expressed on the surface of human plasmacytoid dendritic cells (pDCs). It interacts with bone marrow stromal cell antigen 2 to control the Tolllike receptor (TLR) driven response by pDCs to viral infection. It may also be involved in modulating pDCtumour interactions. pDCs are a source of the excess IFNalpha which drives autoimmune disease symptoms. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 48.5 kDa
• Tag: N-10*His
• NCBI: 59901
• Puffer: PBS, pH7.4
• Reinheit: 95%
• Formulierung: Powder
• Target-Kategorie: LILRA4

Bilder

Immobilized Human LILRA4, His Tag (Cat. No. LI4-H5243) at 2 µg/mL (100 µL/well) can bind Monoclonal Anti-LILRA4 Antibody, Human IgG1 with a linear range of 0.001-0.008 µg/mL (QC tested).

Human LILRA4, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.