Human LILRB4 / CD85k / ILT3 Protein, Fc Tag (MALS verified), Unconjugated

Produktübersicht

• Artikelname: Human LILRB4 / CD85k / ILT3 Protein, Fc Tag (MALS verified), Unconjugated
• Artikelnummer: ABS-LI4-H5256-50UG
• Hersteller Artikelnummer: LI4-H5256-50ug
• Alternativnummer: ABS-LI4-H5256-50UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

Leukocyte immunoglobulinlike receptor subfamily B member 4 (LILRB4) is also known as CD85 antigenlike family member K (CD85K), Immunoglobulinlike transcript 3 (ILT3), Leukocyte immunoglobulinlike receptor 5 (LIR5), Monocyte inhibitory receptor HM18, which belongs to the leukocyte immunoglobulinlike receptor (LIR) family. LILRB4 / CD85K contains 2 Iglike C2type (immunoglobulinlike) domains. CD85K is detected in monocytes, macrophages, dendritic cells, lung, natural killer cells and Bcells. LILRB4 / CD85K is receptor for class I MHC antigens. CD85K recognizes a broad spectrum of HLAA, HLAB, HLAC and HLAG alleles, involved in the downregulation of the immune response and the development of tolerance. LILRB4 interferes with TNFRSF5signaling and NFkappaB upregulation and inhibits receptormediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 52.7 kDa
• Tag: C-Fc
• NCBI: 26309
• Puffer: PBS, pH7.4
• Reinheit: 95%
• Formulierung: Powder
• Target-Kategorie: LILRB4

Bilder

Immobilized Human LILRB4, Fc Tag (Cat. No. LI4-H5256) at 1 µg/mL (100 µL/well) can bind Anti-LILRB4 Antibody, Human IgG1 with a linear range of 0.4-6 ng/mL (QC tested).

Human LILRB4, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.