Mouse LIGHT / TNFSF14 Protein, His Tag, active trimer, low endotoxin (MALS verified), Unconjugated, Human
Artikelnummer:
ABS-LIT-M5243-1MG
Hersteller Artikelnummer:
LIT-M5243-1mg
Alternativnummer:
ABS-LIT-M5243-1MG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Mouse
Konjugation:
Unconjugated
Tumor necrosis factor ligand superfamily member 14(LIGHT) is a tumor necrosis factor (TNF) superfamily ligand that regulates T cell immune responses by signaling through the herpes virus entry mediator (HVEM) and the lymphotoxin beta receptor (LTbetaR). LIGHT has emerged as a potent initiator of T cell costimulation signals effecting CTLmediated tumor rejection, allograft rejection and graft versus host disease. Constitutive expression of LIGHT leads to tissue destruction and autoimmunelike disease syndromes. - Proteine/Peptide