Human LRRC32 / GARP / Garpin Protein, Fc Tag, Unconjugated
Artikelnummer:
ABS-LR2-H5256-1MG
Hersteller Artikelnummer:
LR2-H5256-1mg
Alternativnummer:
ABS-LR2-H5256-1MG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Leucinerich repeat protein 32 (LRRC32), also known as GARP (glycoprotein A repetitions predominant). LRRC32 expression promotes the acquisition of a Treg phenotype including reduced cellular proliferation, reduced cytokine secretion, and the capacity to suppress the proliferation of naive T cells. LRRC32 binds directly to the TGFbeta latency associated peptide (LAP) and tethers latent TGFbeta on the surface of activated Treg cells. The presentation of TGFbeta on Tregs contributes to their ability to suppress naive T cell proliferation. - Proteine/Peptide
