Biotinylated Human LRP-6 (20-630) Protein, His,Avitag(TM)

Artikelnummer: ABS-LR6-H82E7-200UG
Artikelname: Biotinylated Human LRP-6 (20-630) Protein, His,Avitag(TM)
Artikelnummer: ABS-LR6-H82E7-200UG
Hersteller Artikelnummer: LR6-H82E7-200ug
Alternativnummer: ABS-LR6-H82E7-200UG
Hersteller: AcroBiosystems
Wirt: Human
Kategorie: Proteine/Peptide
Spezies Reaktivität: Human
Konjugation: Biotin
LRP6 is a transmembrane lowdensity lipoprotein receptor that shares a similar structure with LRP5. Lowdensity lipoprotein receptorrelated protein 6 is a key component of the LRP5/LRP6/Frizzled coreceptor group that is involved in canonical Wnt pathway. The Wntinduced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3Bcomplex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3mediated phosphorylation and destruction of betacatenin. - Proteine/Peptide
Molekulargewicht: 72.5 kDa
Tag: C-10*His & C-Avi
NCBI: 75581
Puffer: PBS, pH7.4
Expression System: Ala 20 - Pro 630
Reinheit: 90%
Formulierung: Powder
Target-Kategorie: LRP-6
LR6-H82E7-200ug