Human MANF Protein, His Tag (MALS verified), Unconjugated
Artikelnummer:
ABS-MAF-H52H3-20UG
Hersteller Artikelnummer:
MAF-H52H3-20ug
Alternativnummer:
ABS-MAF-H52H3-20UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
MANF is a secreted neurotrophic factor that is expressed in brain, neuronal and certain nonneuronal tissues. It has been shown to promote the survival, growth and function of dopaminespecific neurons. MANF and its structural homolog CDNF each contain a Nterminal, saposinlike, lipidbinding domain, and a carboxylterminal domain that is not homologous to previously characterized protein structures. MANF and CDNF can prevent 6OHDAinduced degeneration of dopaminergic neurons by triggering survival pathways in a rat experimental model of Parkinsons disease. Recombinant Human MANF is an 18.1 kDa protein consisting of 158 amino acids, including 8 cysteine residues. - Proteine/Peptide
Human MANF Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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