Nectin4 (gene name PVRL4, poliovirus receptorlike 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin4 is a tumorassociated antigen in 50%, 49% and 86%o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues. - Proteine/Peptide
Immobilized Anti-Nectin-4 Antibody, Mouse IgG1 at 2 µg/mL (100 µL/well) can bind FITC-Labeled Human Nectin-4, His Tag (Cat. No. NE4-HF2H3) with a linear range of 10-78 ng/mL (QC tested).
NE4-HF2H3-25ug
FITC-Labeled Human Nectin-4, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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