SARS-CoV-2 ORF8 Protein, His Tag (MALS verified), Unconjugated, Human
Artikelnummer:
ABS-OR8-C52H1-100UG
Hersteller Artikelnummer:
OR8-C52H1-100ug
Alternativnummer:
ABS-OR8-C52H1-100UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Virus
Konjugation:
Unconjugated
Alternative Synonym:
sars-cov-2
The viral protein encoded by open reading frame 8 (ORF8) of SARSCoV2, which shares the least homology with SARSCoV among all viral proteins, directly interacts with MHC molecules and mediates their downregulation. In ORF8expressing cells, MHC molecules are selectively targeted for lysosomal degradation via autophagy. Thus, SARSCoV2-infected cells are much less sensitive to lysis by cytotoxic T lymphocytes. - Proteine/Peptide
SARS-CoV-2 ORF8 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
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