Human OX40 Ligand / TNFSF4 Protein, His Tag, active trimer, low endotoxin (MALS verified), Unconjugated
Artikelnummer:
ABS-OXL-H5243-50UG
Hersteller Artikelnummer:
OXL-H5243-50ug
Alternativnummer:
ABS-OXL-H5243-50UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L), TAX transcriptionallyactivated glycoprotein 1 and CD252, which belongs to the tumor necrosis factor family. TNFSF4 is the ligand for CD134 and is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation. The interaction of TNFSF4TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. Furthermore, similar to other TNF superfamily members, membranebound OX40 Ligand (TNFSF4) exists as a homotrimer. Human TNFSF4 shares 46% amino acid sequence identity with its mouse counterpart. - Proteine/Peptide
Immobilized Human OX40 Ligand Protein, His Tag (Cat. No. OXL-H5243) at 2 µg/mL (100 µL/well) can bind Human OX40, Fc Tag (Cat. No. OX0-H5255) with a linear range of 0.1-1 ng/mL (QC tested).
Immobilized Human OX40 Ligand Protein, His Tag (Cat. No. OXL-H5243) at 2 µg/mL (100 µL/well) can bind Human OX40 Protein, Mouse IgG2a Fc Tag (Cat. No. OX0-H5252) with a linear range of 0.2-8 ng/mL (Routinely tested).
Human OX40 Ligand Protein, His Tag on SDS-PAGE under non-reducing (NR) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
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