Human PD-L1 / B7-H1 Protein, Fc Tag (MALS verified), Unconjugated
Artikelnummer:
ABS-PD1-H5258-100UG
Hersteller Artikelnummer:
PD1-H5258-100ug
Alternativnummer:
ABS-PD1-H5258-100UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Programmed cell death 1 ligand 1 (PDL1) is also known as B7H, B7H1, MGC142294, MGC142296, PDL1, PDCD1L1 and PDCD1LG1,which is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses.PDL1 is a cell surface immunoglobulin superfamily with two Iglike domains within the extracellular region and a short cytoplasmic domain. This protein is broadly expressed in the majority of peripheral tissues as well as hematopoietic cells. Interaction between PDL1 and its receptors belonging to the CD28 family of molecules provide both stimulatory and inhibitory signals in regulating T cell activation and tolerance. PDL1 may inhibit ongoing Tcell responses by inducing apoptosis and arresting cellcycle progression. - Proteine/Peptide
