Biotinylated Human PD-L2 / B7-DC Protein, Fc,Avitag(TM) (MALS verified)

Artikelnummer: ABS-PD2-H82F6-200UG
Artikelname: Biotinylated Human PD-L2 / B7-DC Protein, Fc,Avitag(TM) (MALS verified)
Artikelnummer: ABS-PD2-H82F6-200UG
Hersteller Artikelnummer: PD2-H82F6-200ug
Alternativnummer: ABS-PD2-H82F6-200UG
Hersteller: AcroBiosystems
Wirt: Human
Kategorie: Proteine/Peptide
Spezies Reaktivität: Human
Konjugation: Biotin
Programmed cell death 1 ligand 2 (PDL2 or PDCD1 ligand 2) is also known as Butyrophilin B7DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PDL2 is upregulated by IFNG/IFNgamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL4. PDL2 Involved in the costimulatory signal, essential for Tcell proliferation and IFNG production in a PDCD1independent manner. PDL2 interaction with PDCD1 inhibits Tcell proliferation by blocking cell cycle progression and cytokine production. - Proteine/Peptide
Molekulargewicht: 51.0 kDa
Tag: C-Fc & C-Avi
NCBI: 9
Puffer: Tris with Glycine, Arginine and NaCl, pH7.5
Reinheit: 95%
Formulierung: Powder
Target-Kategorie: PD-L2
Immobilized Human PD-1, Fc Tag (Cat. No. PD1-H5257) at 2 µg/mL (100 µL/well) can bind Biotinylated Human PD-L2, Fc,Avitag (Cat. No. PD2-H82F6) with a linear range of 0.5-16 ng/mL (QC tested).
Biotinylated Human PD-L2, Fc,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.