Human PLAU / uPA Protein, His Tag (activated by trypsin) (active enzyme), Unconjugated

Produktübersicht

• Artikelname: Human PLAU / uPA Protein, His Tag (activated by trypsin) (active enzyme), Unconjugated
• Artikelnummer: ABS-PLU-H5228-50UG
• Hersteller Artikelnummer: PLU-H5228-50ug
• Alternativnummer: ABS-PLU-H5228-50UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

Urokinase type plasminogen activator is also known as PLAU and UPA, a serine protease with an extremely limited substrate specificity, cleaving the sequence Cys - Pro - Gly Arg560 Val561 - Val - Gly - Gly - Cys in plasminogen to form plasmin. uPA is a potent marker of invasion and metastasis in a variety of human cancers associated with breast, stomach, colon, bladder, ovary, brain and endometrium.uPA and its receptor (uPAR) have been implicated in a broad spectrum of pathophysiological processes, including fibrinolysis, proteolysis, inflammation, atherogenesis and plaque destabilization, all of which are involved in the pathogenesis of MI (myocardial infarction). - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 15.3 kDa, 17.8 kDa and 29.2 kDa
• Tag: C-6*His
• NCBI: 00749
• Puffer: 25 mM HEPES, 150 mM NaCl, pH7.5
• Reinheit: 90%
• Formulierung: Powder
• Target-Kategorie: PLAU

Bilder

Human PLAU, His Tag (activated by trypsin) on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.