Cynomolgus PSMA / FOLH1 Protein, His Tag (active enzyme, MALS verified), Unconjugated, Human
Artikelnummer:
ABS-PSA-C5247-100UG
Hersteller Artikelnummer:
PSA-C5247-100ug
Alternativnummer:
ABS-PSA-C5247-100UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Monkey
Konjugation:
Unconjugated
Prostatespecific membrane antigen (PSMA) is also known as Folate hydrolase 1 (FOLH1), Glutamate carboxypeptidase 2 (GCP2), Nacetylatedalphalinked acidic dipeptidase I (NAALAD1), which belongs to the peptidase M28 family and M28B subfamily. FOLH1 / PSMA is stable at pH greater than 6.5. FOLH1 / PSMA is a type II transmembrane zinc metallopeptidase that is most highly expressed in the nervous system, prostate, kidney, and small intestine. FOLH1 / GCP2 is homodimer and binds 2 zinc ions per subunit, and required for NAALADase activity. The catalytic activity of PSMA involved in releasing of an unsubstituted, Cterminal glutamyl residue, typically from AcAspGlu or folylpoly - gamma glutamates. FOLH1 / GCP2 / PSMA has both folate hydrolase and N - acetylated - alpha - linked acidic dipeptidase (NAALADase) activity and has a preference for trialphaglutamate peptides. GCP2 / PSMA involved in prostate tumor progression and also exhibits a dipeptidylpeptidase IV type activity. In vitro, cleaves GlyProAMC. - Proteine/Peptide
Immobilized Cynomolgus PSMA, His Tag (Cat. No. PSA-C5247) at 2 µg/mL (100 µL/well) can bind Monoclonal Anti-Human PSMA Antibody, Human IgG1 with a linear range of 0.2-4 ng/mL (QC tested).
Cynomolgus PSMA, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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