Human PTP4A3 Protein, His Tag (MALS verified), Unconjugated, E. coli

Produktübersicht

• Artikelname: Human PTP4A3 Protein, His Tag (MALS verified), Unconjugated, E. coli
• Artikelnummer: ABS-PT3-H5143-50UG
• Hersteller Artikelnummer: PT3-H5143-50ug
• Alternativnummer: ABS-PT3-H5143-50UG
• Hersteller: AcroBiosystems
• Wirt: E. coli
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

PTP4A3 (Protein Tyrosine Phosphatase 4A3) is an oncogenic phosphatase that promotes tumor metastasis by enhancing cell migration, invasion, and survival. It is overexpressed in multiple cancers (e.g., breast, ovarian, colorectal) and correlates with poor prognosis. PTP4A3 activates Rho GTPases and downstream pathways (ROCK/LIMK/cofilin) to remodel the actin cytoskeleton, facilitating cancer cell dissemination. Its dual cysteinebased catalytic domain dephosphorylates key signaling proteins, driving aggressive phenotypes. Targeting PTP4A3 offers therapeutic potential for inhibiting metastasis. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 21.1 kDa
• Tag: N-10*His
• NCBI: 75365
• Puffer: PBS, 0.2 M Arginine, pH7.4
• Reinheit: 90%
• Formulierung: Powder
• Target-Kategorie: PTP4A3

Bilder

Human PTP4A3 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.