Human S100B Protein, His Tag, Unconjugated, E. coli

Produktübersicht

• Artikelname: Human S100B Protein, His Tag, Unconjugated, E. coli
• Artikelnummer: ABS-S1B-H5143-1MG
• Hersteller Artikelnummer: S1B-H5143-1mg
• Alternativnummer: ABS-S1B-H5143-1MG
• Hersteller: AcroBiosystems
• Wirt: E. coli
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

S100 protein beta chain (S100B),a member of the S100 family, is also known as S100 protein subunit beta and S100 calciumbinding protein B, which contains two EFhand domains. S100B can weakly bind calcium but bind zinc very tightlydistinct binding sites with different affinities exist for both ions on each monomer. Also, S100B can bind to and initiate the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction,S100B may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Fuethermore,S100B could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. S100B may mediate calciumdependent regulation on many physiological processes by interacting with other proteins, such as TPRcontaining proteins, and modulating their activity. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 11.5 kDa
• Tag: N-6*His
• NCBI: 006263
• Puffer: 50 mM Tris, 150 mM NaCl, pH8.0
• Reinheit: 95%
• Formulierung: Powder
• Target-Kategorie: S100B

Bilder

Human S100B, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.