Human Semaphorin 4A / SEMA4A Protein, His Tag, Unconjugated
Artikelnummer:
ABS-SEA-H5224-100UG
Hersteller Artikelnummer:
SEA-H5224-100ug
Alternativnummer:
ABS-SEA-H5224-100UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Semaphorin4A (SEMA4A) is also known as SemaphorinB (SEMAB), which belongs to the semaphorin family. SEMA4A contains one Iglike C2type (immunoglobulinlike) domain, one PSI domain and one sema domain. SEMA4A is cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an important role in cellcell signaling. SEMA4A plays a role in priming antigenspecific Tcells, promotes differentiation of Th1 Thelper cells, and thereby contributes to adaptive immunity. SEMA4A also promotes phosphorylation of TIMD2 and inhibits angiogenesis. SEMA4A promotes axon growth cone collapse and inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. - Proteine/Peptide
