Cynomolgus Siglec-10 Protein, His Tag (MALS verified), Unconjugated, Human
Artikelnummer:
ABS-SI0-C52H5-1MG
Hersteller Artikelnummer:
SI0-C52H5-1mg
Alternativnummer:
ABS-SI0-C52H5-1MG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Monkey
Konjugation:
Unconjugated
The siglecs (sialic acidbinding Iglike lectins) are a distinct subset of the Ig superfamily with adhesionmoleculelike structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Iglike domains, a transmembrane domain, and a cytoplasmic tail containing two ITIMsignaling motifs. Siglec10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec10VAP1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products. - Proteine/Peptide
