SARS-CoV-2 Spike Trimer Protein, His Tag (BA.2.86/Denmark/EPI_ISL_18114953+H69V70) (MALS verified), Unconjugated, Human

Produktübersicht

• Artikelname: SARS-CoV-2 Spike Trimer Protein, His Tag (BA.2.86/Denmark/EPI_ISL_18114953+H69V70) (MALS verified), Unconjugated, Human
• Artikelnummer: ABS-SPN-C5220-500UG
• Hersteller Artikelnummer: SPN-C5220-500ug
• Alternativnummer: ABS-SPN-C5220-500UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Virus
• Konjugation: Unconjugated
• Alternative Synonym: sars-cov-2

Produktbeschreibung

SARSCoV2 Spike Trimer Protein, His Tag (BA.2.86/Denmark/EPI_ISL_18114953+H69V70) (SPNC5220) is expressed from human 293 cells (HEK293). It contains AA Val 16 Pro 1213 (Accession QHD43416.1 (ins16MPLF,T19I,R21T,LPP2426Del,A27S,S50L,V127F,G142D,Y144del,F157S,R158G,N211del,L212I,V213G,L216F,H245N,A264D,I332V,G339H,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,N440K,V445H,G446S,N450D,L452W,N460K,S477N,T478K,N481K,V483del,E484). The spike mutations are identified on the SARSCoV2 Omicron variant (Pango lineage: BA.2.86/Denmark/EPI_ISL_18114953+H69V70). The recombinant protein is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the Cterminus. Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) and alanine substitutions (R683A and R685A) are introduced to stabilize the trimeric prefusion state of SARSCoV2 S protein and abolish the furin cleavage site, respectively. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 138.3 kDa
• Tag: C-10*His
• NCBI: 43416
• Puffer: 0.1 M Sodium citrate, pH5.5
• Reinheit: 90%
• Formulierung: Powder
• Target-Kategorie: Spike protein

Bilder

Immobilized Human ACE2, Fc Tag (Cat. No. AC2-H5257) at 5 µg/mL (100 µL/well) can bind SARS-CoV-2 Spike Trimer Protein, His Tag (BA.2.86/Denmark/EPI_ISL_18114953+H69V70) (Cat. No. SPN-C5220) with a linear range of 0.5-31 ng/mL (QC tested).

SARS-CoV-2 Spike Trimer Protein, His Tag (BA.2.86/Denmark/EPI_ISL_18114953+H69V70) on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.