SARS-CoV-2 Spike Trimer Protein (T19R, G142D, EF156-157del, R158G, L452R, T478K, D614G, P681R, D950N), His Tag (MALS verified), Unconjugated, Human

Produktübersicht

• Artikelname: SARS-CoV-2 Spike Trimer Protein (T19R, G142D, EF156-157del, R158G, L452R, T478K, D614G, P681R, D950N), His Tag (MALS verified), Unconjugated, Human
• Artikelnummer: ABS-SPN-C52HE-50UG
• Hersteller Artikelnummer: SPN-C52He-50ug
• Alternativnummer: ABS-SPN-C52HE-50UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Virus
• Konjugation: Unconjugated
• Alternative Synonym: sars-cov-2

Produktbeschreibung

SARSCoV2 Spike Trimer, His Tag (SPNC52He) is expressed from human 293 cells (HEK293). It contains AA Val 16 Pro 1213 (Accession QHD43416.1). The mutations (T19R, G142D, EF156157del, R158G, L452R, T478K, D614G, P681R, D950N) were identified in the SARSCoV2 Delta variant (Pango lineage: B.1.617.2, other names: 21A/S:478K). The recombinant protein is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the Nterminus. Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) and alanine substitutions (R683A and R685A) are introduced to stabilize the trimeric prefusion state of SARSCoV2 S protein and abolish the furin cleavage site, respectively. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 137.8 kDa
• Tag: C-10*His
• NCBI: 43416
• Puffer: 0.1 M Sodium citrate, pH5.5
• Reinheit: 95%
• Formulierung: Powder
• Target-Kategorie: Spike protein

Bilder

Immobilized SARS-CoV-2 Spike Trimer, His Tag (Cat. No. SPN-C52He) at 1 µg/mL (100 µL/well) can bind Human ACE2, Fc Tag (Cat. No. AC2-H5257) with a linear range of 0.2-2 ng/mL (QC tested).

Immobilized SARS-CoV-2 Spike Trimer, His Tag (Cat. No. SPN-C52He) at 1 µg/mL (100 µL/well) can bind Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (Cat. No. S1N-M122) with a linear range of 0.1-2 ng/mL (Routinely tested).

SARS-CoV-2 Spike Trimer, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.