SARS-CoV-2 Spike Trimer Protein (T19R, G142D, EF156-157del, R158G, L452R, T478K, D614G, P681R, D950N), His Tag (MALS verified), Unconjugated, Human
Artikelnummer:
ABS-SPN-C52HE-50UG
Hersteller Artikelnummer:
SPN-C52He-50ug
Alternativnummer:
ABS-SPN-C52HE-50UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Virus
Konjugation:
Unconjugated
Alternative Synonym:
sars-cov-2
SARSCoV2 Spike Trimer, His Tag (SPNC52He) is expressed from human 293 cells (HEK293). It contains AA Val 16 Pro 1213 (Accession QHD43416.1). The mutations (T19R, G142D, EF156157del, R158G, L452R, T478K, D614G, P681R, D950N) were identified in the SARSCoV2 Delta variant (Pango lineage: B.1.617.2, other names: 21A/S:478K). The recombinant protein is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the Nterminus. Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) and alanine substitutions (R683A and R685A) are introduced to stabilize the trimeric prefusion state of SARSCoV2 S protein and abolish the furin cleavage site, respectively. - Proteine/Peptide