Human Stathmin 1 / STMN1 Protein, His Tag, Unconjugated, E. coli
Artikelnummer:
ABS-ST1-H5149-100UG
Hersteller Artikelnummer:
ST1-H5149-100ug
Alternativnummer:
ABS-ST1-H5149-100UG
Hersteller:
AcroBiosystems
Wirt:
E. coli
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Stathmin (STMN1), a member of the stathmin family, is also known as Leukemiaassociated phosphoprotein p18, Oncoprotein 18 (Op18), Phosphoprotein p19 (pp19), Protein Pr22 and pp17, which contains one SLD (stathminlike) domain. The function of STMN1 as an important regulatory protein of microtubule dynamics has been wellcharacterized. Stathmin (STMN1) interacts with two molecules of dimeric alpha,betatubulin to form a tight ternary complex called the T2S complex.One mole of STMN1 binds to two moles of tubulin dimers through the stathminlike domain (SLD).When STMN1 sequesters tubulin into the T2S complex, tubulin becomes nonpolymerizable. Without tubulin polymerization, there is no microtubule assembly.STMN1 also promotes microtubule disassembly by acting directly on the microtubule ends. - Proteine/Peptide
