Human TDP-43 Protein, His Tag, Unconjugated, E. coli

Produktübersicht

• Artikelname: Human TDP-43 Protein, His Tag, Unconjugated, E. coli
• Artikelnummer: ABS-TD3-H5145-500UG
• Hersteller Artikelnummer: TD3-H5145-500ug
• Alternativnummer: ABS-TD3-H5145-500UG
• Hersteller: AcroBiosystems
• Wirt: E. coli
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

TDP43, the transactive response (TAR)DNA binding Protein with a molecular weight of 43 KDa is encoded by TARDBP gene that located at the chromosome 1. It is a RNA/DNA binding protein that structurally resembles a typical hnRNP protein family member. involved in transcriptional regulation and RNA processing. It is linked to sporadic and familial amyotrophic lateral sclerosis and frontotemporal lobar degeneration. TDP43 is predominantly nuclear, but it translocates to the cytoplasm under pathological conditions. Cytoplasmic accumulation, phosphorylation, ubiquitination and truncation of TDP43 are the main hallmarks of TDP43 proteinopathies. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 46.8 kDa
• Tag: N-10*His
• NCBI: 13148
• Puffer: 50 mM HEPES, 500 mM NaCl, 0.4 M Arginine, pH8.0
• Expression System: Met 1 - Met 414
• Reinheit: 90%
• Formulierung: Liquid
• Target-Kategorie: TDP-43

Bilder

TD3-H5145-500ug