Mouse Thrombopoietin R Protein, His Tag, Unconjugated, Human
Artikelnummer:
ABS-THR-M52H4-100UG
Hersteller Artikelnummer:
THR-M52H4-100ug
Alternativnummer:
ABS-THR-M52H4-100UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Mouse
Konjugation:
Unconjugated
Thrombopoietin R, also known as TPOR, is expressed predominantly on the surface of MKs, platelets, hemangioblasts, and hematopoietic stem cells (HSCs). Binding of TPO to the megakaryocyte TPOR leads to different effects: prevention of megakaryocyte apoptosis, increased megakaryocyte number, size, and ploidy, increasing rate of megakaryocyte maturation, and internalization of the TPO/TPOR complex. Thrombopoietin R involved in multiple signal transduction pathways, such as JAK, STAT, and MAP kinase. - Proteine/Peptide
