Biotinylated Porcine Thrombopoietin R Protein, His,Avitag(TM), Human
Artikelnummer:
ABS-THR-P82E3-25UG
Hersteller Artikelnummer:
THR-P82E3-25ug
Alternativnummer:
ABS-THR-P82E3-25UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Porcine
Konjugation:
Biotin
Thrombopoietin R, also known as TPOR, is expressed predominantly on the surface of MKs, platelets, hemangioblasts, and hematopoietic stem cells (HSCs). Binding of TPO to the megakaryocyte TPOR leads to different effects: prevention of megakaryocyte apoptosis, increased megakaryocyte number, size, and ploidy, increasing rate of megakaryocyte maturation, and internalization of the TPO/TPOR complex. Thrombopoietin R involved in multiple signal transduction pathways, such as JAK, STAT, and MAP kinase. - Proteine/Peptide