Biotinylated Mouse TIGIT Protein, Fc,Avitag(TM) (MALS verified), Human

Produktübersicht

• Artikelname: Biotinylated Mouse TIGIT Protein, Fc,Avitag(TM) (MALS verified), Human
• Artikelnummer: ABS-TIT-M82F3-200UG
• Hersteller Artikelnummer: TIT-M82F3-200ug
• Alternativnummer: ABS-TIT-M82F3-200UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Mouse
• Konjugation: Biotin

Produktbeschreibung

Tcell immunoreceptor with Ig and ITIM domains (TIGIT) is also known as Vset and immunoglobulin domaincontaining protein 9 (VSIG9), Vset and transmembrane domaincontaining protein 3 (VSTM3),which belongs to singlepass type I membrane protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosinebased inhibitory motif (ITIM). TIGIT is expressed at low levels on peripheral memory and regulatory CD4+ Tcells and NK cells and is upregulated following activation of these cells (at protein level). TIGIT binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses Tcell activation by promoting the generation of mature immunoregulatory dendritic cells. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 41.1 kDa
• Tag: C-Fc & C-Avi
• NCBI: 0
• Puffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
• Reinheit: 90%
• Formulierung: Powder
• Target-Kategorie: TIGIT

Bilder

Immobilized Biotinylated Mouse TIGIT Protein, Fc,Avitag (Cat. No. TIT-M82F3) at 1 µg/mL (100 µL/well) on streptavidin precoated (Cat. No.STN-N5116) can bind Mouse CD155, Mouse IgG2a Fc Tag (Cat. No. CD5-M5254) with a linear range of 0.2-8 ng/mL (QC tested).

Biotinylated Mouse TIGIT Protein, Fc,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.