Human CD30 / TNFRSF8 Protein, Llama IgG2b Fc Tag, low endotoxin, Unconjugated

Artikelnummer: ABS-TN8-H5250-1MG
Artikelname: Human CD30 / TNFRSF8 Protein, Llama IgG2b Fc Tag, low endotoxin, Unconjugated
Artikelnummer: ABS-TN8-H5250-1MG
Hersteller Artikelnummer: TN8-H5250-1mg
Alternativnummer: ABS-TN8-H5250-1MG
Hersteller: AcroBiosystems
Wirt: Human
Kategorie: Proteine/Peptide
Spezies Reaktivität: Human
Konjugation: Unconjugated
Human CD30 is also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. TNFRSF8 is expressed by activated, but not by resting, T and B cells. Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15. CD30 is the receptor for TNFSF8/CD30L. CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NFkappaB. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. - Proteine/Peptide
Molekulargewicht: 66.3 kDa
Tag: C-LlamaFc(LlamaIgG2b)
NCBI: 001234
Puffer: Tris with Glycine, Arginine and NaCl, pH7.5
Reinheit: 95%
Formulierung: Powder
Target-Kategorie: CD30
TN8-H5250-1mg
Immobilized Human CD30 Protein, Llama IgG2b Fc Tag (Cat. No. TN8-H5250) at 0.5 µg/mL (100 µL/well) can bind Anti-CD30 Mab, Human IgG1 with a linear range of 0.1-1.6 ng/mL (QC tested).
Human CD30 Protein, Llama IgG2b Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.