Human TREM-1 / CD354 Protein, Fc Tag, Unconjugated
Artikelnummer:
ABS-TR1-H5251-1MG
Hersteller Artikelnummer:
TR1-H5251-1mg
Alternativnummer:
ABS-TR1-H5251-1MG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Triggering receptor expressed on myeloid cells 1 (TREM1) is also known as CD antigen CD354, and is a type I transmembrane protein with a single Iglike domain. TREM1 is highly expressed in adult liver, lung and spleen than in corresponding fetal tissue. TREM1 / CD354 stimulates neutrophil and monocytemediated inflammatory responses, and also triggers release of proinflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock. TREM1 can interacts with TYROBP / DAP12. - Proteine/Peptide